Summary of key evidence. That was a lie. That work has yielded one promising candidate, the antidepressant fluvoxamine; other CETF-funded efforts have been less successful. It is currently approved for treatment of depression and obsessive compulsive disorder (OCD). Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Death Signal, Mystery Clots Embed 7.76K 31 'This Has Cost Millions Of Lives': Steve Kirsch On Suppression Of Repurposed Drugs And A Spike In Deaths 5 Months After Vaccine Rollout By Jan Jekielek American Thought Leaders / The Epoch Times November 24, 2022 Show more Hes also recently increased the number of Americans he claim have been killed by the vaccine from 25,0000, to 150,000, or even as many as 250,000 Americans. That way you can start immediately. Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI), a class of anti-depressants, mostly prescribed for people suffering from an obsessive-compulsive disorder. Keeping this drug off the NIH Guidelines does nothing to reduce the death rate. Ive used it personally at 50mg twice a day and experience no adverse events at all. By March 2020, hed settled on the idea of searching for covid treatments in the pre-existing pharmacopeia. An approach that promised to democratize design may have done the opposite. If you start later, doctors use higher dosages and compliance becomes a bigger problem. One of the drugs, Fluvoxamine, showed a 30 . He started 7 high tech companies, two with billion dollar market caps. You see this with people who have a lot of money, who think that reflects their intelligence, Richman told me. The ICER independent review showed fluvoxamine is more effective than Molnupiravir: Read this article I wrote about using fluvoxamine correctly for COVID. Most doctors wont use it until NIH greenlights it, no matter what the science says. It's hard to ignore this lecture in explaining why the drug is so effective. He pushes fluvoxamine, an anti-depression drug which despite doing very well in covid treatment studies has been strangely neglected. One user reported dilated pupils and increased heart rate (which could be nerves about the dilated pupils). ALWAYS check with your doctor and report any medications you are taking before or plan to take after you start taking fluvoxamine. The drugs mechanisms of action were explained to the KOL panel which voted 2>1 in favor of fluvoxamine. Skirsch.io Steve Kirsch Home page Fluvoxamine, COVID, pandemic, . One is to reduce the threat of nuclear war. Here are my answers. And he wont talk to you either if you ask nosy questions like Cliff, my risk benefit analysis shows you should be rushing to recommend this drug. Sadly, doctors and public health officials refuse to instruct patients to seek early treatment. We have a bounty of vaccines and more on the way, but drugs that treat the disease are vital too if we want to keep people alive and bring the pandemic under control. How can the FDA say a drug which meets the gold standard of evidence has insufficient evidence? The NIH picks the drug that makes the most money for the drug companies regardless of long-term safety Molnupiravir! The NIH never did a risk benefit analysis of this drug. Steve Kirsch is looking for an explanation for 171,000 excess deaths. Stopping the meds will return you to your normal self. Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI), a class of anti-depressants, mostly prescribed for people suffering from an obsessive-compulsive disorder. Most recent articles first. The man who ran Risperdal sales, Alex Gorsky, is now CEO of Johnson & Johnson. Nobody who took the drug got sick at all, most all wanted to return to work within 3 days after starting treatment. There is an executive summary below, but the most important thing is that top infectious disease docs who have looked at all the evidence (including the two clinical trial results) believe the effect size is 75% or more in reducing the hospitalization rate. Ive talked to doctors who are extremely familiar with the drug and all the trial results and they would prescribe it to their patients. The combined p value of the two studies is <.0001. The incident, he added, was completely in keeping with his personality.. But they will refuse to give it to you even after being proven in a Phase 3 trial that was approved by the WHO. The trials that were abandoned for futility werent getting events because the patients were given standard of care meds. I couldn't agree more. Fluvoxamine public data repository - Google Drive, On Cytokines, Fluvoxamine and COVID-19 Part 1, Jon-Emile S. Kenny MD[@heart_lung] You see, we have a kind of allergy to the past; its our national disease, and the very assurance with which you insist that the past is within the present is l, On Cytokines, Fluvoxamine and COVID-19 Part 2, Jon-Emile S. Kenny MD[@heart_lung] Apocalypse is played out now on a personal scale; it is not in the sky above us, but in our bed. -Mark Doty Introduction With a proposed pathway coupling patho, Effect of Fluvoxamine vs Placebo on Clinical Deterioration in Outpatients With Symptomatic COVID-19, This randomized trial compares the effects of fluvoxamine, a selective serotonin reuptake inhibitor with immunomodulatory effects vs placebo on a composite of dyspnea or pneumonia and oxygen desaturation among adult outpatients with polymerase chain reactionconfirmed mild coronavirus disease 2019 (, Prospective cohort of fluvoxamine for early treatment of COVID-19, Abstract. Since FLV is a safe drug, it should have been widely discussed with patients that there is virtually no downside and a huge reduction in hospitalization if the drug is given early. The FDA approved Molnupiravir which was less effective. It was tested in. So check the side-effects list to be familiar with which side-effects are associated with which drug so if you have a side-effect, youll know which drug to reduce or eliminate. are all super cheap, effective, and available without a prescription. 1. Article about the rejection (Stat News) Article about the fluvoxamine rejection (The Verge) NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). People who report not tolerating the drug are typically prescribed too high a dose. $1M reward: Do we need more data re: Fluvoxamine for COVID-19? Jeffrey Glenn, an infectious disease professor at Stanford University, calls the inaction on the current evidence on the table "criminal.". The reason that it isnt used is because the medical community ignores evidence-based medicine principles. O, Platelet reactivity to thrombin differs between patients with COVID-19 and those with ARDS unrelated to COVID-19 | Blood Advances | American Society of Hematology, Fluvoxamine for COVID-19 summary Steve Kirsch Executive Director COVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008, Fluvoxamine for COVID-19 Steve Kirsch Executive Director COVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008, Drug Repurposing Research Leads to Potentially Game-Changing Treatment to Prevent Clinical Deterioration in Outpatients With COVID, The Covid-19 Early Treatment Fund was launched to provide funding for research in order to, Steve Kirschs answer to What is the current treatment for Covid-19? and here are the slides I used in, Collections of op-eds and presentations about fluvoxamine, Please see my answer on Quora In June, after CETFs advisory board resigned, Kirsch did a Facebook Live video with Zelenko and celebrity rehab coach Dr. Drew. . From the French observational data (see the very last page), it appears that the biggest effect is limiting serotonin release (any SSRI will do that). So you can address your OCD and if you get COVID, youll can up the dose. The sooner you start, the better the outcomes. The WashU Phase 3 study hasnt been disclosed yet, but they had compliance problems with their patients this time around (phase 2 was local so the patients got the drug early and also were very compliant and the placebo group was truly taking nothing). Most recent articles first. All this was known back in January 2021 when a key opinion leader panel of experts from NIH, CDC, FDA, academia, and journal editors voted by over 2:1 to recommend that fluvoxamine be recommended to physicians to discuss with patients. This looks ominous, but it harmless. Adverse reactions/side effects. In September, Kirsch emailed Morris asking him to estimate the maximum number of deaths caused by vaccines. He started a covid-19 vaccine company. None of this would really matter if Kirschs views on vaccinations were private, or shared with a limited audience. Kirsch: Yes, but you could easily watch that 60 Minutes story and believe that we need more data before people should start using fluvoxamine. Ivermectin and fluvoxamine have been confirmed in Phase 3 trials. Skirsch.io site visitors volume is 1,957 unique day-to-day guests and their 3,914 pageviews. If you cant lay off the java, then try fluoxetine (Prozac). You will be wired for 24 hours if you dont heed my advice. Entrepreneur Steve Kirsch who holds an early patent for the optical mouse decided to get involved in treating Covid. After one or two conversations like that, I got tired of arguing, so I started avoiding his calls.. Some countries dont have fluvoxamine so this is the alternative. Fluvoxamine has a 40 year safety track record. Note that some of these articles are inaccurate. Some people are jittery, but usually that is because the doctor either prescribed a dosage higher than 50mg twice a day or didnt notify the patient to. Get your prescription in advance of getting COVID. If you ask your doctor for any evidence that fluvoxamine doesnt work or is harmful (like a DB-RCT which is the only thing they trust), they will show you nothing. It should be crystal clear to everyone that the current CDC guidelines for treating COVID aren't working. Medicine today isnt about saving your life. Completely avoid caffeine, alcohol, tylenol, and benadryl. P-value was 10^-14 on that study (done by Dr. Seftel). If the drug is started right after symptoms, weve seen 100% prevention in hospitalization. It is in a class of drugs known as selective serotonin-reuptake inhibitors (SSRIs), but unlike other SSRIs, fluvoxamine interacts strongly with a protein called the sigma-1 receptor. Even though they spent only 45 minutes and just reviewed the 2 clinical studies and some plausible mechanisms of action (and ignored anecdotal evidence and multiple retrospective trials, all of which were supportive), after the meeting they voted overwhelmingly (11 to 5 with 4 being neutral) in favor of having doctors talk to their patients about using fluvoxamine if they have COVID using a "shared decision making" process. Saving the world has been a theme of Kirschs life for years. Ms Tech | Pexels (hands); Kirsch (skirsch.com), Ivermectin has been falsely promoted as a covid treatmentbut for those who use the drug legitimately, seeing it become a piece of anti-vaccine misinformation is disconcerting, supports Technology Review's reporting on covid, anti-covid-vaccine, pro-ivermectin pundit, Roomba testers feel misled after intimate images ended up on Facebook, How Rust went from a side project to the worlds most-loved programming language. The other doctors aren't using it either because they don't know about it or fear doing anything not approved by the CDC for treating COVID. Hes also publicly railed against what he claims is a campaign against drugs like fluvoxamine and ivermectin. Dr. Eric Lenze: So the results were really pretty. The NIH Guidelines committee is being very slow to react (we have no idea if they are even considering the drug because nobody is allowed to know that because all their deliberations are kept secret). They knew in advance it was coming and on the day the paper was published they ignored it entirely. I have all of these on hand and I load up on vitamin D3 every day. Where did it go wrong. If you do have a side-effect, it is usually mild nausea which goes away when you stop taking the drug. How covid-19 conspiracy videos keep getting millions of views. But not 150K. This is the gold standard of evidence based medicine. We asked Steve to tone it down. I didnt intend to spend a lot of time on Steve in particular, but that video was so influential.. He might be a good snake oil salesman., I experienced this myself when, on one call, we discussed several studies. The medical community doesnt care about saving lives. So you can address your OCD and if you get COVID, youll can up the dose. I couldnt tell I was on the drug. Over the next few years, millions of unvaccinated people are going to get covid; its vital to try to mitigate their suffering, as well as lessen pressure on the health care system. Ive talked to doctors who are extremely familiar with the drug and all the trial results and they would prescribe it to their patients. I have never heard of a case it didn't work. You can help by bringing this document to your doctor's attention. David Boulware, a researcher at the University of Minnesota, received $125,000 to test the drug against covid. Everyone says "we need more data" to show fluvoxamine works for COVID. There are reports of people who cant tolerate the drug, but they stop using it and nothing bad happened. There are other non-prescription things you should always have on hand. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. Fluvoxamine is the poster child of the COVID-19 Early Treatment Fund (CETF). Get your prescription in advance of getting COVID. The reason is pure corruption. Indeed, some of the most prominent people spreading misinformation about ivermectin and vaccines today began by promoting hydroxychloroquineincluding by claiming to debunk Boulwares data analysis. Everyone is stunned, but nobody is surprised. With covid, 80% of your patient population does just peachy with no treatment at all, just a little bed rest and fluid. Proxalutamide and fluvoxamine pushers and the early treatment grift. has tons of info on fluvoxamine with all the links. Jan 17. And, according to three members of CETF's scientific advisory board, he put pressure on them to promote fluvoxamine for clinical use without conclusive data that it worked for . Generally, at 50mg BID x 14, it is very tolerable as long as the patient is instructed to lay off the caffeine. Most recent articles first. I think so. Decreasing the dosage or stopping the medication will mitigate symptoms within hours. Server IP address resolved: Yes Http response code: 200 Response time: 0.27 sec. Dose escalation studies in lupus patients and in rheumatoid arthritis patients established that 800 mg per day for life and 1,200 mg per day for 6 weeks are extremely well-tolerated. In the early days of the pandemic, as billions of dollars poured into the hunt for novel treatments and vaccines, veteran Silicon Valley entrepreneur Steve Kirsch did what hes always done: He went looking for an underdog. You will be wired for 24 hours if you dont heed my advice. As a health care journalist, I started off firmly in the wait-and-see camp on mRNA vaccines. Steve Kirsch Executive Director at COVID-19 Early Treatment Fund (2020-present) Author has 176 answers and 1.7M answer views Updated 1 y Both. Comparison with molnupiravir. In every case we are aware of, the drug was successful in reversing COVID symptoms, generally in 3 days or less. Doctors who have used fluvoxamine in the US and other countries swear by it. Kirsch did a lot of things right when he set up CETF. Fluvoxamine - The backstory T he i nsi de st ory behi nd how f l uvoxami ne became a CO V I D t herapy By Steve Kirsch Last updated: June 3, 2021 . See the repository above. Di scl ai mer: T he vi ews expressed i n t hi s art i cl e are my own personal opi ni on based on my 1, 000+ hour st udy of cut t i ng edge . They rejected the drug for insufficient evidence just like they always do for ivermectin. Be warned!. Try refreshing this page and updating them one Peter Meinke, another former board member, spent nearly three decades in drug discovery at Merck. this is NOT about the science. It has enrolled only 130 people in the first month and is enrolling only 70 per week now. As of November 13, fluvoxamine has been proven to work in every trial that has published results, including outpatient and inpatient studies. By Steve Kirsch Mar 14, 2021 Fluvoxamine, Proxalutamide, and Ivermectin: 100% success I'm very bullish on two drug combos since it is rare for a single drug to be 100% successful. NIH and WHO refuse to acknowledge it works since it will cause vaccine hesitancy if it is known that there is a drug that turns COVID into a mild disease. More recently, hes adopted extremist positions on covid vaccines, which he alleges are toxic. He has claimed that one in 1,000 people who have received mRNA vaccines have died as a result, and even claimed the vaccines kill more people than they save at an FDA public forum, which was first reported by the Daily Beast. My website. ). As Kirsch has gone deeper into the anti-vaccine scene, many professional associates have increasingly distanced themselves from him. Its actually much harder to parse out a signal than if youre treating diabetes or cancer., In addition to the issues with fluvoxamine, advisors grew increasingly uncomfortable with Kirschs posts about ivermectin, which he has repeatedly claimed in blog posts and appearances in alternative media can be used together with fluvoxamine to prevent 100% of covid-19 deaths. Some speaker, off camera, went on a . He prefers iconoclastic approaches, whether by directly funding asteroid detection or advocating for nuclear power to combat global warming. Compulsive fiddling with your mask? CETF Founder Steve Kirsch discusses why we can't wait for a COVID-19 vaccine, the importance of researching existing drugs now, and our work to raise funds for outpatient trials to identify effective . So check the side-effects list to be familiar with which side-effects are associated with which drug so if you have a side-effect, youll know which drug to reduce or eliminate. Theres nothing there.). Paper reviewing the evidence and mechanisms of action for fluvoxamine: Lenze Phase 2 RCT published Nov 12, 2020: Seftel RWE trial that confirmed the Phase 2 trial published Feb 1, 2021. ALWAYS check with your doctor and report any medications you are taking before or plan to take after you start taking fluvoxamine. Hes refused to accept the results of a hydroxychloroquine trial that showed the drug had no value in treating covid, for instance, instead blaming investigators for poor study design and statistical errors. Also, for people who cant tolerate fluvoxamine for whatever reason (nausea, jittery, etc), this is the alternative. I mean, he really, truly has a heart of gold, Char told me. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. Steve is a Silicon Valley entrepreneur and philanthropist who founded the COVID-19 Early Treatment Fund (CETF) at the beginning of the pandemic. The CDC has advised everyone to wear a mask. He thinks # killed by vax could be anywhere between 0 and 150K people dead.. Kirsch is a serial entrepreneur who has spent decades pitching the next big thing, whether optical mice (Mouse Systems), document processing (FrameMaker), search engines (Infoseek), digital. The medical community doesnt care about saving lives. This document is a collection of evidence that highlights the glaring errors in our pandemic response. skirsch.io Steve Kirsch Home page. The race to find covid-19 drug treatments that actually work, The antimalarial drug Trump took for covid might actually be dangerous. Reason is the hospital gets release from liability if they follow NIH guidelines. 12:45 AM . All this was known back in January 2021 when a key opinion leader panel of experts from NIH, CDC, FDA, academia, and journal editors voted by over 2:1 to recommend that fluvoxamine be recommended to physicians to discuss with patients. The 5 observational studies is icing on the cake. Jeffrey Morris, director of biostatistics at the University of Pennsylvania Perelman School of Medicine, has made debunking Kirschs claims something of a hobby. I was just getting tired, he said, before asking to speak off the record. No long haul symptoms if you start the drug ASAP after first symptoms. Doctors have no excuse for not prescribing. Added to FLCCC protocols and Fareed-Tyson protocol among others. We pretty much practice government agency opinion medicine all over the world now, with just a few exceptions. Fluvoxamine works on hospitalized patients too, but no US hospital will let you use it (sound familiar? Fluvoxamine at 50mg twice a day for 14 days is a very well-tolerated drug (as long as you avoid caffeine and alcohol) for the treatment of COVID infections. It was 25 years ago yesterday that Andrew Wakefield launched the modern iteration of the antivaccine movement.In doing so, he laid down a template that antivax quacks today still follow. If you continue to get this message, The track management was so impressed, they asked for prescriptions. See my article on treatments. Fluvoxamine, COVID, pandemic, . Nov 12: Steve Kirsch gives talk on CETF to HarvardBusiness School hosted by Dr. Seftel Nov 13:Mass COVID outbreak at GGF is now publiclyknown Nov 16: Seftel, the track physician at GGF, startsFLV . . Doctors wait for government permission (EUA or added to the NIH guidelines) before using a drug. Thanks to the volumes of data and information provided by pharmaceutical companies and regulators, as well as large numbers of trials from independently funded research groups around the world, I now trust that theyre safe for the vast majority of adults. He applied the drug to a large COVID outbreak at Golden Gate Fields just days after the Lenze trial was published. This post was written to memorialize the corruption. Kirsch told me that meta-analyses are a higher level of evidence than randomized controlled trials. When I responded that meta-analyses are only as good as the data they are based on, he said Id like to understand your source on that, because I cant find a source that says a phase 3 trial is greater evidence than a meta-analysis., When you characterize me, you need to say that Steve Kirsch doesn't go with majority votes on interpreting data.. My favorite dosage is 50mg twice a day for 14 days. I also think it makes a lot of sense to look for pre-existing drugs that can help treat covid symptoms. CETF was founded by entrepreneur and philanthropist Steve Kirsch, as a way to expedite the fight against COVID-19. (Siliciano did not respond to requests for comment for this article.). Soon after his appearance on the DarkHorse podcast, several partners of his most recent startup, M10, expressed concerns about the increasing extremism of Kirschs vaccine views. upcoming events, and more. Our in-depth reporting reveals whats going on now to prepare you for whats coming next. Don't underestimate the virus. . Steve Kirsch reported that doctors commonly say (of fluvoxamine), "This is the most powerful drug in my arsenal. just like ivermectin). The alarming article cited the claims of two anti-vaxxers, Steve Kirsch and Dr. Robert Malone. The External Medicine Podcast - Fluvoxamine as a potential treatment for COVID-19: An Interview with Steve Kirsch. Last Checked: 03/02/2023. In a recent post, discussing claims Kirsch made during a three-minute comment at an FDA public forum, Morris wrote: In spite of many pages of writing and claims of over a dozen independent analyses verifying their results, their evidence falls far short of substantiating these dramatic conclusions, including a claim that vaccines have caused >250K excess deaths in the USA.. Im taking low dosage Fluvoxamine as part of a multi-drug FLCCC protocol to alleviate some mild brain fog. His appearance on an episode of anti-covid-vaccine, pro-ivermectin pundit Bret Weinsteins DarkHorse podcast, alongside Robert Malone, a prominent source of vaccine misinformation, introduced Kirsch to followers of the intellectual dark web, who have since embraced him as a fellow truth-teller. Three of the four outpatient trials have been reported out: all were successful. The US government accused Janssen of improperly promoting the antipsychotic drug Risperdal to dementia patients despite the drug increasing deaths in the elderly. The NIH wrote a bullshit rejection because the FDA told them not to approve it. So how did a man once intent on furthering science become a source of misinformation that undermines the very research he funded? Steve Kirsch is a high-tech serial entrepreneur based in Silicon Valley. . fluvoxamine The fast, easy, safe, simple, low cost treatment for COVID that has worked 100% of the time to prevent hospitalization that nobody wants to talk about We now have a viable solution to reduce COVID hospitalization and mortality; Read More fluvoxamine Got COVID?